Pennington Biomedical Research Center of the Louisiana State University System, Baton Rouge, Louisiana, USA. Weill Cornell Medicine Comprehensive Weight Control Center, New York, New York, USA. Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Frederiksberg C, Denmark. Department of Medicine, Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts, USA. Department of Pediatrics and Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA. Obesity, Metabolism, and Nutrition Institute and Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. Scripps Clinic Del Mar, San Diego, California, USA. Health & Care, sro., Prague, Czech Republic. Third Internal Clinic, Charles University, Prague, Czech Republic. Department of Endocrinology and Metabolism, Policlinico San Donato, University of Milan, Milan, Italy. Experimental Medicine Department, Sapienza University of Rome, Rome, Italy. Center for Nutrition Research, University of Navarra, Pamplona, Spain. CIBERobn and IMDEA Food Institute, Madrid, Spain. Center for Nutrition and Weight, Geisinger Obesity Institute, Danville, Pennsylvania, USA. Gelesis, Inc., Boston, Massachusetts, USA.